Thalidomide-NH-C4-NH-Boc
CAT:
804-HY-130639-03
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Thalidomide-NH-C4-NH-Boc
- CAS Number: 2093388-52-2
- UNSPSC Description: Thalidomide-NH-C4-NH-Boc (compound 15) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
- Target Antigen: Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
- Type: Reference compound
- Related Pathways: Apoptosis;Autophagy;PROTAC
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/thalidomide-nh-c4-nh-boc.html
- Purity: 99.64
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(OC(C)(C)C)NCCCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
- Molecular Weight: 444.48
- References & Citations: [1]Jiang F, et al.Discovery of novel small molecule induced selective degradation of the bromodomain and extra-terminal (BET) bromodomain protein BRD4 and BRD2 with cellular potencies.Bioorg Med Chem. 2020 Jan 1;28(1):115181.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, protect from light)
- Clinical Information: No Development Reported