Thalidomide-NH-amido-C4-Br

• UNSPSC Description:

  Thalidomide-NH-amido-C4-Br is a conjugate of the E3 ligase ligand and the linker, that can be used for synthesis of PROTAC degrader BSJ-02-162 (HY-144995)[1].

• Target Antigen:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/thalidomide-nh-amido-c4-br.html

• Smiles:

  O=C(NCCCCBr)CNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O

• Molecular Weight:

  465.30

• References & Citations:

  [1]Nathanael S. Gray, et al. Degradation of cyclin-dependent kinase 4/6 (cdk4/6) by conjugation of cdk4/6 inhibitors with e3 ligase ligand and methods of use. WO2020023480 A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3027457-50-4