Products for Research Use Only
RegisterLogin

BGC-20-1531

CAT: 0804-HY-W394717Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-W394717Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
BGC-20-1531 (PGN 1531), a benzenesulfonamide derivative, is a selective EP4 antagonist. BGC-20-1531 binds to PGE2 enhancing the ATPase activity, which are coupled to Gs proteins and thus activate adenylate cyclase generating cAMP and activating PKA. BGC-20-1531 is promising for research of liver disorders[1][2].
CAS Number
1186532-61-5
Product Name Alternative
PGN 1531
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PKA; Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Stem Cell/Wnt; TGF-beta/Smad
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/bgc-20-1531.html
Smiles
O=C(C1=CC(COC2=CC=C(C3=NC=C(C=C3)OC)C=C2)=C(C)O1)N([Na])S(=O)(C4=C(C)C=CC=C4)=O
Molecular Formula
C26H23N2NaO6S
Molecular Weight
514.53
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Ammazzalorso A, et al. N-acylsulfonamides: Synthetic routes and biological potential in medicinal chemistry. Chem Biol Drug Des. 2017 Dec;90 (6) :1094-1105.|[2]Hodeify R, et al. PGE2 upregulates the Na+/K+ ATPase in HepG2 cells via EP4 receptors and intracellular calcium. PLoS One. 2021 Jan 14;16 (1) :e0245400.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
EP

Related Products

CatalogName
HY-107047BGC-201259
HY-146917S20:0-20:1-20:0 TG-d5
HY-W450672-0120-Methoxy-20-oxoicosanoic acid
HY-W034597-0120- (tert-Butoxy) -20-oxoicosanoic acid
HY-N1487620-Deoxysalinomycin
HY-175244SOS1-IN-20
HY-131960BPolysucrose 20
HY-176212Ferroptosis-IN-20
HY-160186-0120-SOLA
HY-159585CYP51-IN-20

Alternative Products

CatalogName
LEB18335-01BGC-20-1531
MDD92826-01Bgc 20-1531 hydrochloride
GTR19185345-01BGC-20-1531 free base
5327/10BGC 20-1531 hydrochloride 10 mg
T8993L-01BGC-20-1531 hydrochloride (1186532-61-5 free base)
B7366-10BGC 20-761
584174BGC-20-761
MBS5811818BGC-638
MBS3603079-01BGC20-1531
sc-53494ERβ (1531)

Popular Products