MMA-NODAGA

• UNSPSC Description:

  MMA-NODAGA is a chelator for site-specific labeling of targeting proteins containing unpaired cysteine. MMA-NODAGA can be used to conjugate with exosome and 64Cu in image with positron emission tomography (PET)[1].

• Target Antigen:

  Radionuclide-Drug Conjugates (RDCs)

• Type:

  Reference compound

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/mma-nodaga.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(CN1CCN(CCN(C(CCC(NCCN2C(C=CC2=O)=O)=O)C(O)=O)CC1)CC(O)=O)O

• Molecular Weight:

  497.50

• References & Citations:

  [1]Sara F F Almeida , et al. Osteosarcoma-Derived Exosomes as Potential PET Imaging Nanocarriers for Lung Metastasis. Small. 2022 Dec;18(49):e2203999. |[2]Mohamed Altai, et al. Influence of nuclides and chelators on imaging using affibody molecules: comparative evaluation of recombinant affibody molecules site-specifically labeled with ⁶⁸Ga and ¹¹¹In via maleimido derivatives of DOTA and NODAGA. Bioconjug Chem. 2013 Jun 19;24(6):1102-9.

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  No Development Reported

• CAS Number:

  1440903-11-6