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Hedragonic acid

CAT: 0804-HY-N4063Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N4063Size:1 Each
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Description
Hedragonic acid is an oleane-type triterpenoid compound, which can be isolated from the stems and roots of the southern snake vine. Hedragonic acid is a ligand and agonist for FXR. Hedragonic acid protected mice from liver damage caused by acetaminophen overdose and reduced liver inflammation[1].
CAS Number
466-02-4
UNSPSC
12352211
Target
FXR
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hedragonic-acid.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12C([C@@]3([H])[C@](C(O)=O)(CCC(C)(C)C3)CC2)=CC[C@@]4([H])[C@]1(CC[C@]([C@@H]5C)([H])[C@@]4(CCC5=O)C)C
Molecular Formula
C29H44O3
Molecular Weight
440.66
References & Citations
[1]Lu Y, et al. Identification of an Oleanane-Type Triterpene Hedragonic Acid as a Novel Farnesoid X Receptor Ligand with Liver Protective Effects and Anti-inflammatory Activity. Mol Pharmacol. 2018 Feb;93 (2) :63-72.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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