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Recombinant Human METTL3

CAT: 0710-P0737-01Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0710-P0737-01Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
AdoMet-binding subunit of the human mRNA (N6-adenosine) -methyltransferase, IME4, M6A, Methyltransferase like protein 3, Methyltransferase-like protein 3, METTL3, mRNA (2'-O-methyladenosine-N (6) -) -methyltransferase, mRNA m (6) A methyltransferase, MT-A70
UniProt
Q86U44
Expression Region
397-580
Host
E.Coli
Tag
N-terminal His-IF2DI Tag
Applications
Western Blot, ELISA
Field of Research
Neuroscience, Metabolism
Purity
Greater than 90% as determined by SDS-PAGE.
Form
Lyophilized powder
Reconstitution
Centrifuge the vial before opening, reconstitute in sterile distilled water to a concentration of 0.1-1 mg/ml by gently pipetting 2-3 times, don't vortex.
Molecular Weight
41.8 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
The lyophilized protein is stable at -20 °C for up to 1 year. For extended storage, it is recommended to further dilute in working aliquots after reconstitution. The protein solution is stable at ≤ -20 °C for 3 months, or 2-7 days at 2-8 °C under sterile conditions.Avoid repeated freeze/thaw cycle.
Formulation
Lyophilized from a 0.2 μm filtered solution of 10 mM Hepes, 150 mM NaCl with 5% trehalose, pH 7.4.
Organism Species
Human

UniProtKB · Q86U44

N(6)-adenosine-methyltransferase catalytic subunit METTL3

MTA70_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q86U44
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
METTL3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.1.1.348
Processing
—
Secondary accessions
O14736, Q86V05, Q9HB32
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

Biological rhythmsDifferentiationDNA damageImmunityInnate immunityOogenesisSpermatogenesis

Cellular component

CytoplasmNucleus

Molecular function

MethyltransferaseRNA-bindingTransferase

Ligand

S-adenosyl-L-methionine

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