GLUT4-IN-2
CAT:
804-HY-146980-06
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
GLUT4-IN-2
- CAS Number: 2454113-83-6
- UNSPSC Description: GLUT4-IN-2 is a potent and selective GLUT4 inhibitor with IC50s of 11.4 μM and 6.8 μM for GLUT1 and GLUT4, respectively. GLUT4-IN-2 induces cell apoptosis and cell cycle arrest at G0/G1phase. GLUT4-IN-2 shows potent antitumor activity[1].
- Target Antigen: Apoptosis; GLUT
- Type: Reference compound
- Related Pathways: Apoptosis;Membrane Transporter/Ion Channel
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/glut4-in-2.html
- Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 80°C)
- Smiles: O=C(NC1=NC2=CC=CC=C2S1)CN(C/3=O)C(SC3=C\C4=CC=CO4)=O
- Molecular Weight: 385.42
- References & Citations: [1]Tilekar K,et al. Structure guided design and synthesis of furyl thiazolidinedione derivatives as inhibitors of GLUT 1 and GLUT 4, and evaluation of their anti-leukemic potential. Eur J Med Chem. 2020 Sep 15;202:112603.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported