GLUT4-IN-2

CAT: 0804-HY-146980-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-146980-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
GLUT4-IN-2 is a potent and selective GLUT4 inhibitor with IC50s of 11.4 μM and 6.8 μM for GLUT1 and GLUT4, respectively. GLUT4-IN-2 induces cell apoptosis and cell cycle arrest at G0/G1phase. GLUT4-IN-2 shows potent antitumor activity[1].
CAS Number
[2454113-83-6]
UNSPSC
12352005
Target
Apoptosis; GLUT
Type
Reference compound
Related Pathways
Apoptosis; Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/glut4-in-2.html
Purity
99.17
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O=C(NC1=NC2=CC=CC=C2S1)CN(C/3=O)C(SC3=C\C4=CC=CO4)=O
Molecular Formula
C17H11N3O4S2
Molecular Weight
385.42
References & Citations
[1]Tilekar K, et al. Structure guided design and synthesis of furyl thiazolidinedione derivatives as inhibitors of GLUT 1 and GLUT 4, and evaluation of their anti-leukemic potential. Eur J Med Chem. 2020 Sep 15;202:112603.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
GLUT1; GLUT4

Related Products

CatalogName
HY-174145GLUT4 activator 3
HY-P80689-01Glucose Transporter GLUT4 Antibody (Rabbit)
HY-P80495-01Glucose Transporter GLUT4 Antibody (YA753, Mouse)
HY-P84098-01Glucose Transporter GLUT4 Antibody (YA3795, Mouse)
HY-P86894Glucose Transporter GLUT4 Antibody (YA6587, Rabbit)
HY-148315-01GLUT1-IN-2
HY-W011060-01Cryptand 2.2.2
HY-B1500-012,2,2-Trichloroethanol
HY-B1500R-012,2,2-Trichloroethanol (Standard)
HY-132268-01Cav 2.2 blocker 2

Alternative Products

CatalogName
M35582-01GLUT4-IN-2
PA1039-SGLUT4
E2347063Glut4/Glucose Transporter GLUT4 Rabbit pAb
MBS8586382-01Glut4 Antibody
536781-01Glut4 discontinued

Popular Products