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Evenamide (hydrochloride)

CAT: 0804-HY-17612ASize: 1 EachDry Ice: NoHazardous: No
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Description
Evenamide hydrochloride is an orally available voltage-gated sodium channel (VGSC) blocker (Ki=0.4 μM) for the research of schizophrenia. Evenamide hydrochloride shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness[1][2].
CAS Number
1092977-06-4
Product Name Alternative
NW-3509 (hydrochloride)
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/evenamide-hydrochloride.html
Smiles
O=C(CNCCC1=CC=CC(OCCCC)=C1)N(C)C.Cl
Molecular Formula
C16H27ClN2O2
Molecular Weight
314.85
References & Citations
[1]Valentina Zuliani, et al. Advances in Design and Development of Sodium Channel Blockers. Ion Channels and Their Inhibitors pp 79-115.|[2]Faravelli, et al. P.3.f.022 Evenamide (formerly NW-3509) targets new mechanisms, and represents a new approach to the management of untreated symptoms in schizophrenia.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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