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Evenamide

CAT: 0804-HY-17612-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-17612-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Evenamide (NW-3509) is an orally available voltage-gated sodium channel (VGSC) blocker (Ki=0.4 μM) for the research of schizophrenia. Evenamide shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness[1][2].
CAS Number
1092977-61-1
Product Name Alternative
NW-3509
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/evenamide.html
Purity
96.45
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N(C)C)CNCCC1=CC=CC(OCCCC)=C1
Molecular Formula
C16H26N2O2
Molecular Weight
278.39
References & Citations
[1]Valentina Zuliani, et al. Advances in Design and Development of Sodium Channel Blockers. Ion Channels and Their Inhibitors pp 79-115.|[2]Faravelli, et al. P.3.f.022 Evenamide (formerly NW-3509) targets new mechanisms, and represents a new approach to the management of untreated symptoms in schizophrenia.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

Alternative Products

CatalogName
BUP01388-01Evenamide
GTR19197661-01Evenamide HCl

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