Gly-β-MCA

CAT: 0804-HY-114392-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-114392-01Size:5 mg
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Description
Gly-β-MCA, a bile acid, is a potent, sable, intestine-selective and oral bioactive farnesoid X receptor (FXR) inhibitor that may be a candidate for the treatment of metabolic disorders[1].
CAS Number
[66225-78-3]
Product Name Alternative
Y-39983 (free base)
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; FXR
Type
Reference compound
Related Pathways
Autophagy; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Gly-​_beta_-MCA.html
Purity
99.95
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)
Smiles
C[C@@H]([C@@]1([H])CC[C@@]2([H])[C@@]3([H])[C@]([C@]4(CC[C@@H](O)C[C@H]4[C@H](O)[C@@H]3O)C)([H])CC[C@]12C)CCC(NCC(O)=O)=O
Molecular Formula
C26H43NO6
Molecular Weight
465.62
Precautions
H302, H315, H319, H335
References & Citations
[1]Jiang C, et al. Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction. Nat Commun. 2015 Dec 15;6:10166.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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