MCA-d3

CAT: 0804-HY-W027544SSize: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-W027544SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MCA-d3 (7-Methoxycoumarin-4-acetic acid3) is the deuterium labeled MCA (HY-W027544) [1]. MCA is a Coumarin (HY-N0709) derivative. MCA quantitates platelet-activating factor (PAF) by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities[2][3].
Product Name Alternative
7-Methoxycoumarin-4-acetic acid-d3
UNSPSC
12352005
Target
Fluorescent Dye; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Others
Solubility
10 mM in DMSO
Smiles
O=C1OC2=C(C(CC(O)=O)=C1)C=CC(OC([2H])([2H])[2H])=C2
Molecular Formula
C12H7D3O5
Molecular Weight
237.22
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Perera NC, et, al. NSP4 is stored in azurophil granules and released by activated neutrophils as active endoprotease with restricted specificity. J Immunol. 2013 Sep 1;191 (5) :2700-7.|[3]Choi YH, et, al. Effect of functional groups on the solubilities of coumarin derivatives in supercritical carbon dioxide. Chromatographia. 1998 Jan47 (93-7) .
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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