MCA-d3

• Description :

  MCA-d3 (7-Methoxycoumarin-4-acetic acid3) is the deuterium labeled MCA (HY-W027544) [1]. MCA is a Coumarin (HY-N0709) derivative. MCA quantitates platelet-activating factor (PAF) by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities[2][3].

• Product Name Alternative :

  7-Methoxycoumarin-4-acetic acid-d3

• UNSPSC :

  12352005

• Target :

  Fluorescent Dye; Isotope-Labeled Compounds

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Others

• Field of Research :

  Others

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1OC2=C(C(CC(O)=O)=C1)C=CC(OC([2H])([2H])[2H])=C2

• Molecular Formula :

  C12H7D3O5

• Molecular Weight :

  237.22

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Perera NC, et, al. NSP4 is stored in azurophil granules and released by activated neutrophils as active endoprotease with restricted specificity. J Immunol. 2013 Sep 1;191 (5) :2700-7.|[3]Choi YH, et, al. Effect of functional groups on the solubilities of coumarin derivatives in supercritical carbon dioxide. Chromatographia. 1998 Jan47 (93-7) .

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported