Mouse anti Human Neuron-Specific Enolase

Mouse anti Human Neuron-Specific Enolase

• Background: Enolases have been characterized as highly conserved cytoplasmic glycolytic enzymes that may be involved in differentiation. Three isoenzymes have been identified, Enolase, Enolase and Enolase. Enolase expression has been detected on most tissues, whereas Enolase is expressed predominantly in muscle tissue and Enolase is detected only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway.
• Synonyms: ENO2, Enolase 2, (gamma, neuronal), 2-Phospho-D-GlyceRate Hydrolase
• CAS Number: 9007-83-4
• UniProt: P09104
• Host: Mouse
• Species Reactivity: Human, Mouse, Chicken
• Isotype: IgG1
• Clone: NSE-P2
• Conjugation: Unconjugated
• Type: Monoclonal Antibody
• Applications: WB, ELISA, IHC
• Purification Method: Protein A/G Chromatography
• Assay Principle: Antibody can be used for Western blotting (1-2 µg/mL) and immunohistochemistry on formalin-fixed, paraffin-embedded tissue sections (1-5µg/mL). Optimal concentration should be evaluated by serial dilutions.
• Stability: See expiration date on vial
• Concentration: See vial for Concentration
• Form: Provided as solution in phosphate buffered saline with 0,08% sodium azide
• Precautions: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals.
• References & Citations: 1. Kang, J.L., et al. (1996). Immunoreactive neuron-specific enolase (NSE) is expressed in testicular carcinoma-in-situ. J. Pathol. 178(2):161-165. 2. Koch, M., et al. (2007). Plasma S100beta and NSE levels and progression in multiple sclerosis. J. Neurol. Sci. 252(2):154-158. 3. Oertel, M., et al. (2006). S-100B and NSE: markers of initial impact of subarachnoid haemorrhage and their relation to vasospasm and outcome. J. Clin. Neurosci. 13(8):834-840.
• Shipping Conditions: Ambient Temperature, freeze upon arrival
• Storage Conditions: Product should be stored at -20ºC; Aliquot to avoid freeze/thaw cycles
• Functional Analysis: WB