c-Fms-IN-13

• UNSPSC Description:

  c-Fms-IN-13 (compound 14) is a potent FMS kinase inhibitor with an IC50 value of 17 nM. c-Fms-IN-13 can be used as an anti-inflammatory agent[1].

• Target Antigen:

  c-Fms

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/c-fms-in-13.html

• Solubility:

  DMSO : 31.25 mg/mL (ultrasonic)

• Smiles:

  N#CC1=CC=C(C(NC2=CC=C(N3CCCCC3)C=C2N4CCCCC4)=O)O1

• Molecular Weight:

  378.47

• References & Citations:

  [1]Illig CR, et al. Discovery of novel FMS kinase inhibitors as anti-inflammatory agents. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1642-8.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  885704-58-5