BOS-172722
CAT:
804-HY-112162-05
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
BOS-172722
- CAS Number: 1578245-44-9
- UNSPSC Description: BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint with an IC50 of 11 nM and 63 nM for MPS1 (1 mM ATP) and P-MPS1, respectively. BOS-172722 also has potential for the study of various forms of breast cancer[1].
- Target Antigen: Mps1
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;Cytoskeleton
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/BOS-172722.html
- Purity: 98.65
- Solubility: 1M HCl : 65 mg/mL (ultrasonic;adjust pH to 2 with HCl)|DMSO : < 1 mg/mL
- Smiles: CC1=CC2=CN=C(NC3=CC=C(C4=NN=CN4C)C=C3OCC)N=C2C(NCC(C)(C)C)=N1
- Molecular Weight: 446.55
- References & Citations: [1]ARYL SULFONOHYDRAZIDES. WO 2014037750 A1.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: Phase 1