4-Hydroxymidazolam

• UNSPSC Description:

  4-Hydroxymidazolam is a major metabolite of Midazolam. Midazolam is a potent benzodiazepine with anxiolytic properties.

• Target Antigen:

  Drug Metabolite; GABA Receptor

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/4-Hydroxymidazolam.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC1C2=CN=C(C)N2C3=CC=C(Cl)C=C3C(C4=CC=CC=C4F)=N1

• Molecular Weight:

  341.77

• References & Citations:

  [1]Seo KA, et al. Metabolism of 1'- and 4-hydroxymidazolam by glucuronide conjugation is largely mediated by UDP-glucuronosyltransferases 1A4, 2B4, and 2B7. Drug Metab Dispos. 2010 Nov;38(11):2007-13.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  59468-85-8