α-Synuclein 4554W

• UNSPSC Description:

  α-Synuclein 4554W is an inhibitor of α-Synuclein (aSyn) aggregation with associated toxicity. α-Synuclein 4554W consists of GIVNGVKA sequences, previously identified through intracellular library screening. α-Synuclein 4554W reduces fibril formation of aSyn mutants assocaited with Parkinson’s disease[1].

• Target Antigen:

  α-synuclein

• Type:

  Peptides

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/α-synuclein-4554w.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NC([C@H](C)NC([C@H](CCCCN)NC([C@H](C(C)C)NC(CNC([C@H](CC(N)=O)NC([C@H](C(C)C)NC([C@H]([C@@H](C)CC)NC(CNC([C@H](CC(O)=O)NC([C@@H](NC(C)=O)CCCCN)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Weight:

  1041.20

• References & Citations:

  [1]Torpey J H, et al. Insights into peptide inhibition of alpha-synuclein aggregation[J]. Frontiers in Neuroscience, 2020, 14: 561462.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2243207-00-1