Dyrk1A/α-synuclein-IN-2
CAT:
804-HY-144696
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Dyrk1A/α-synuclein-IN-2
- CAS Number: 2789711-66-4
- UNSPSC Description: Dyrk1A/α-synuclein-IN-2 (Compound b20) is a dual Dyrk1A and α-synuclein aggregation inhibitor with an IC50 of 7.8 µM for α-synuclein. Dyrk1A/α-synuclein-IN-2 has high predictive CNS penetration and neuroprotective effect[1].
- Target Antigen: DYRK
- Type: Reference compound
- Related Pathways: Protein Tyrosine Kinase/RTK
- Applications: Neuroscience-Neurodegeneration
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/dyrk1a-α-synuclein-in-2.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(NC1=NC2=C(S1)C=C(C=C2)O)NC3=CC=C(C=C3)NC(C4=CC(O)=CC=C4)=O
- Molecular Weight: 420.44
- References & Citations: [1]AlNajjar, et al. Discovery of novel 6-hydroxybenzothiazole urea derivatives as dual Dyrk1A/α-synuclein aggregation inhibitors with neuroprotective effects. European journal of medicinal chemistry 227 (2022): 113911.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported