Dyrk1A/α-synuclein-IN-1

CAT:

804-HY-144695

Size:

Inquire

Price:

Ask

For price, please contact [email protected]

CAS Number: 2789711-47-1
UNSPSC Description: Dyrk1A/α-synuclein-IN-1 (Compound b1) is a dual Dyrk1A and α-synuclein aggregation inhibitor with IC50 values of 177 nM and 10.5 µM, respectively. Dyrk1A/α-synuclein-IN-1 has high predictive CNS penetration and neuroprotective effect[1].
Target Antigen: DYRK
Type: Reference compound
Related Pathways: Protein Tyrosine Kinase/RTK
Applications: Neuroscience-Neurodegeneration
Field of Research: Neurological Disease
Assay Protocol: https://www.medchemexpress.com/dyrk1a-α-synuclein-in-1.html
Solubility: 10 mM in DMSO
Smiles: O=C(NC1=NC2=C(S1)C=C(C=C2)O)NC3=CC=C(C=C3)NC(C4CCNCC4)=O
Molecular Weight: 411.48
References & Citations: [1]AlNajjar, et al. Discovery of novel 6-hydroxybenzothiazole urea derivatives as dual Dyrk1A/α-synuclein aggregation inhibitors with neuroprotective effects. European journal of medicinal chemistry 227 (2022): 113911.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-144695	Dyrk1A/α-synuclein-IN-1
HY-144696	Dyrk1A/α-synuclein-IN-2
HY-156435	tau Protein/α-synuclein-IN-1
HY-139830	Dyrk1A-IN-1
HY-169288	α-Synuclein modulator 1
HY-159945	tau Protein/α-synuclein-IN-2
HY-160116-02	α-Synuclein aggregate binder 1
HY-160116-01	α-Synuclein aggregate binder 1
HY-160116-06	α-Synuclein aggregate binder 1
HY-146337	Dyrk1A/B-IN-1