CD4, Mouse (T-Cell Marker)

CD4, Mouse (T-Cell Marker)

• Gene Name: [CD4]
• NCBI Gene ID: 12504
• Reactivity: Mouse
  Does not react with Human.
• Storage Conditions: Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: CD4 is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase, lck. CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally.This antibody blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.
• Other Gene Names: [Cd4; Cd4; L3T4; Ly-4]
• Short Name: [CD4]
• Other Product Names: [T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 antigen; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; CD_antigen: CD4]
• NCBI GI Number: 7304953
• NCBI Accession Number: NP_038516.1
• NCBI GB Accession Number: NP_038516.1
• Uniprot Accession Number: P06332