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CD4, Mouse (T-Cell Marker)

CAT: 0544-MBS4381534-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
CAT#:0544-MBS4381534-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[CD4]
NCBI Gene ID
12504
Reactivity
Mouse
Does not react with Human.
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
CD4 is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase, lck. CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally.This antibody blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.
Other Gene Names
[Cd4; Cd4; L3T4; Ly-4]
Short Name
[CD4]
Other Product Names
[T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 antigen; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; CD_antigen: CD4]
NCBI GI Number
7304953
NCBI Accession Number
NP_038516.1
NCBI GB Accession Number
NP_038516.1
Uniprot Accession Number
P06332

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