CD4, Mouse (T-Cell Marker)

• Gene Name:

  [CD4]

• NCBI Gene ID:

  12504

• Reactivity:

  Mouse
  Does not react with Human.

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  CD4 is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase, lck. CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally.This antibody blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.

• Other Gene Names:

  [Cd4; Cd4; L3T4; Ly-4]

• Short Name:

  [CD4]

• Other Product Names:

  [T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 antigen; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; CD_antigen: CD4]

• NCBI GI Number:

  7304953

• NCBI Accession Number:

  NP_038516.1

• NCBI GB Accession Number:

  NP_038516.1

• Uniprot Accession Number:

  P06332