GLUT-1 (Tumor Progression and Mesothelioma Marker)

• Gene Name:

  [GLUT-1]

• NCBI Gene ID:

  6513

• Reactivity:

  Human. Others not known.

• Storage Conditions:

  Antibody with azide - store at 2 to 8 degree C.
  Antibody without azide - store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Recognizes a protein of 55kDa, which is identified as GLUT-1. Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designated as Glut-1 to Glut-12. Glut-1 is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut-1 is expressed at variable levels in many human tissues. Overexpression of Glut-1 has been linked to tumor progression or poor survival of patients with carcinomas of the colon, breast, cervical, lung, bladder and mesothelioma. Glut-1 is a sensitive and specific marker for the differentiation of malignant mesothelioma (positive) from reactive mesothelium (negative).

• Other Gene Names:

  [SLC2A1; SLC2A1; CSE; PED; DYT9; GLUT; DYT17; DYT18; EIG12; GLUT1; HTLVR; GLUT-1; SDCHCN; GLUT1DS; GLUT1; GLUT-1]

• Short Name:

  [GLUT-1]

• Other Product Names:

  [solute carrier family 2, facilitated glucose transporter member 1; Solute carrier family 2, facilitated glucose transporter member 1; solute carrier family 2, facilitated glucose transporter member 1; solute carrier family 2 member 1; Glucose transporter type 1, erythrocyte/brain; GLUT-1; HepG2 glucose transporter]

• NCBI GI Number:

  166795299

• NCBI Accession Number:

  NP_006507.2

• NCBI GB Accession Number:

  NM_006516.3

• Uniprot Accession Number:

  P11166