Tenascin C (Stromal Marker For Epithelial Malignancy)

Tenascin C (Stromal Marker For Epithelial Malignancy)

• Gene Name: [TNC]
• NCBI Gene ID: 3371
• Reactivity: Human.
  Does not react with rat. Others not known.
• Storage Conditions: Antibody with azide - store at 2 to 8 degree C.
  Antibody without azide - store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: In Western blotting, it reacts with two bands of ~MW of 210kDa and 300kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linked hexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.
• Other Gene Names: [TNC; TNC; GP; JI; TN; HXB; GMEM; TN-C; DFNA56; 150-225; HXB; TN; TN-C]
• Short Name: [Tenascin C]
• Other Product Names: [tenascin; Tenascin; tenascin; tenascin C; Cytotactin; GMEM; GP 150-225; Glioma-associated-extracellular matrix antigen; Hexabrachion; JI; Myotendinous antigen; Neuronectin; Tenascin-C; TN-C]
• NCBI GI Number: 153946395
• NCBI Accession Number: NP_002151.2
• NCBI GB Accession Number: NM_002160.3
• Uniprot Accession Number: P24821