Tenascin C (Stromal Marker for Epithelial Malignancy)

• Gene Name:

  [TNC]

• NCBI Gene ID:

  3371

• Reactivity:

  Human
  Does not react with Rat.

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  In Western blotting, it reacts with two bands of ~MW of 210kDa and 300kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linkedhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.

• Other Gene Names:

  [TNC; TNC; GP; JI; TN; HXB; GMEM; TN-C; DFNA56; 150-225; HXB; TN; TN-C]

• Short Name:

  [Tenascin C]

• Other Product Names:

  [tenascin; Tenascin; tenascin; tenascin C; Cytotactin; GMEM; GP 150-225; Glioma-associated-extracellular matrix antigen; Hexabrachion; JI; Myotendinous antigen; Neuronectin; Tenascin-C]

• NCBI GI Number:

  153946395

• NCBI Accession Number:

  NP_002151.2

• NCBI GB Accession Number:

  NP_002151.2

• Uniprot Accession Number:

  P24821