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Procaine

CAT: 0804-HY-B0546-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0546-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Procaine is a DNA-demethylating agent. Procaine acts through multiple targets and has a slow onset and a short duration of action[1][2].
CAS Number
59-46-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bacterial; DNA/RNA Synthesis; Histone Demethylase
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/procaine.html
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(OCCN(CC)CC)C1=CC=C(N)C=C1
Molecular Formula
C13H20N2O2
Molecular Weight
236.31
Precautions
H302, H315, H319, H335
References & Citations
[1]Fan, P. and F.F. Weight, Procaine impairs the function of 5-HT3 receptor-ion channel complex in rat sensory ganglion neurons. Neuropharmacology, 1994. 33 (12) : p. 1573-9.|[2]Villar-Garea, A., et al., Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells. Cancer Res, 2003. 63 (16) : p. 4984-9.|[3]Adamec, R.E. and C. Stark-Adamec, The effects of procaine HCl on population cellular and evoked response activity within the limbic system of the cat. Evidence for differential excitatory action of procaine in a variety of limbic circuits. Prog Neuropsychopharmacol Biol Psychiatry, 1987. 11 (4) : p. 345-64.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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