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Promazine

CAT: 0804-HY-B1225ASize: 1 EachDry Ice: NoHazardous: No
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Description
Promazine (Romtiazin) is an antipsychotic and a dopamine receptor D2 antagonist. Promazine inhibits dopaminergic neurotransmission[1][2].
CAS Number
58-40-2
Product Name Alternative
Romtiazin; Ampazine; Berophen
UNSPSC
12352005
Hazard Statement
H302
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/promazine.html
Solubility
10 mM in DMSO
Smiles
CN(C)CCCN1C2=C(C=CC=C2)SC3=CC=CC=C13
Molecular Formula
C17H20N2S
Molecular Weight
284.42
Precautions
P264-P270-P330-P501
References & Citations
[1]Myers PR, et al. Characterization of a depolarizing dopamine response in a vertebrate neuronal somatic cell hybrid. J Cell Physiol. 1977;91 (1) :103-118. |[2]Gareri P, et al. Conventional and atypical antipsychotics in the elderly : a review. Clin Drug Investig. 2003;23 (5) :287-322. |[3]Tatsumi M, et al. Pharmacological profile of neuroleptics at human monoamine transporters. Eur J Pharmacol. 1999;368 (2-3) :277-283.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
D2 Receptor

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