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HOME2 rabbit pAb

CAT: 0855-ES15690-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES15690-01Size:50 µL
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Background
This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein is a postsynaptic density scaffolding protein. Alternative splicing results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 14. [provided by RefSeq, Jun 2011]
Description
This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein is a postsynaptic density scaffolding protein. Alternative splicing results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 14. [provided by RefSeq, Jun 2011],
Product Name Alternative
Homer protein homolog 2 (Homer-2) (Cupidin)
UniProt
Q9NSB8
Swiss Prot
Q9NSB8
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human HOME2 AA range: 17-67
Target
HOME2
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Molecular Weight
38kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
38kD
Fragment
IgG
Subcellular Location
Cytoplasm . Cell membrane . Cell junction, synapse, postsynaptic density. Cell junction, synapse. Cell projection, stereocilium . Postsynaptic density of neuronal cells. The stabilization and clustering of the metabotropic glutamate receptors appears to be mediated by isoform 1 and isoform 2 at the cell surface.
Other Product Names
Homer protein homolog 2 (Homer-2) (Cupidin)
Gene ID (Human)
9455

UniProtKB · Q9NSB8

Homer protein homolog 2

HOME2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NSB8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HOMER2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Homer-2
EC number
—
Processing
—
Secondary accessions
O95269, O95349, Q9NSB6, Q9NSB7, Q9UNT7
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneCell projectionCytoplasmMembraneSynapse

Domain

Coiled coil

Disease

DeafnessDisease variantNon-syndromic deafness

Biological process

Hearing

Technical term

Proteomics identificationReference proteome