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PHYLPA-8

CAT: 0804-HY-160983Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-160983Size:1 Each
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Description
PHYLPA-8 is an inhibitor for DNA polymerase-α, which exhibits weak inhibitory activity for the stereochemistry of the fatty acid moiety and the cyclic phosphate[1].
CAS Number
169736-88-3
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/phylpa-8.html
Smiles
CCCCCCCC/C=C\CCCCCCCC(OC[C@@H]1COP(O1)(O[Na])=O)=O
Molecular Formula
C21H38NaO6P
Molecular Weight
440.49
References & Citations
[1]Murakami-Murofushi K, et al., Selective inhibition of DNA polymerase-alpha family with chemically synthesized derivatives of PHYLPA, a unique Physarum lysophosphatidic acid. Biochim Biophys Acta. 1995 Aug 24;1258 (1) :57-60.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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