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SOD2 Polyclonal Antibody

CAT: 0763-D-AB-10436L-01Size: 25 µLDry Ice: NoHazardous: No
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CAT#:0763-D-AB-10436L-01Size:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Superoxide dismutases (SOD) are important anti-oxidant enzymes that guard against superoxide toxicity. In humans, as in all mammals and most chordates, three forms of superoxide dismutase (SOD) are present: SOD1 is located in the cytoplasm, SOD2 in the mitochondria, and SOD3 is extracellular. Mitochondrial superoxide dismutase [SOD; manganese SOD (MnSOD) or SOD2] neutralizes highly reactive superoxide radical (O?-2), the first member in the plethora of mitochondrial reactive oxygen species.
Abbreviation
SOD2
UniProt
P04179
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human SOD2 protein expressed by E.coli
Target
Superoxide dismutase [Mn]; mitochondrial; EC:1.15.1.1; SOD2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cell Biology; Cardiovascular; Metabolism; Neuroscience; Signal Transduction
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IHC 1:400-1:800
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
25 kDa
Observed Molecular Weight
25 kDa
Isotype
IgG

UniProtKB · P04179

Superoxide dismutase [Mn], mitochondrial

SODM_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P04179
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SOD2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.15.1.1
Processing
Precursor
Secondary accessions
B2R7R1, B3KUK2, B4DL20, B4E3K9, E1P5A9, P78434, Q16792, Q5TCM1, Q96EE6, Q9P2Z3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationNitrationUbl conjugation

Coding sequence diversity

Alternative splicing

Ligand

ManganeseMetal-binding

Cellular component

Mitochondrion

Molecular function

Oxidoreductase

Domain

Transit peptide
Product Datasheet
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