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Piccolo Antibody (RPE)

CAT: 0013-GTR18029391Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18029391Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to Picollo (RPE) . Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains. In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones) . Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1..
Product Name Alternative
Protein piccolo, Aczonin, PCLO, Presynaptic cytomatrix protein, Multidomain presynaptic cytomatrix protein, Piccolo (presynaptic cytomatrix protein), PCLO_HUMAN, ACZ, Pico, Brain-derived HLMN protein, DKFZp779G1236, KIAA0559, Piccolo mouse homolog of Pico
UniProt
Q9Y6V0
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Full length Protein, BC001304.1
Target
Piccolo
Clonality
Polyclonal
Conjugation
RPE
Field of Research
Metabolism Research
Purification
Protein A Purified
Concentration
1 mg/ml
Dilution
WB (1:1000), IHC (1:400)
Molecular Weight
550kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
1 μg/ml was sufficient for detection of Piccolo in 10 μg of rat brain tissue lysate by colorimetric immunoblot analysis using goat ant rabbit IgG:HRP as the secondary antibody.
Tested Applications
IHC, WB
NCBI Accession Number
NP_055325.2
Host or Source
Rabbit
Preservative
95.46mM Phosphate, 2.48mM MES and 2mM EDTA
Entrez
27445

UniProtKB · Q9Y6V0

Protein piccolo

PCLO_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y6V0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PCLO
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A4D1A7, A6NNX9, O43373, O60305, Q08E72, Q9BVC8, Q9UIV2, Q9Y6U9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

CalciumCalcium/phospholipid-bindingMetal-bindingZinc

Cellular component

Cell projectionSynapse

Disease

Neurodegeneration

PTM

Phosphoprotein

Domain

RepeatZinc-finger

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