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Piccolo Antibody (APC)

CAT: 0013-GTR18028555Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18028555Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mouse monoclonal to Piccolo (APC) . Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains. In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones) . Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1..
Product Name Alternative
Protein piccolo, Aczonin, PCLO, Presynaptic cytomatrix protein, Multidomain presynaptic cytomatrix protein, Piccolo (presynaptic cytomatrix protein), PCLO_HUMAN, ACZ, Pico, Brain-derived HLMN protein, DKFZp779G1236, KIAA0559, Piccolo mouse homolog of Pico
UniProt
Q9QYX7
Reactivity
Human, Mouse, Rat
Immunogen
Full length recombinant protein (GenBank ID: BC001304.1)
Target
Piccolo
Clonality
Monoclonal
Clone
6H9-B6
Conjugation
APC
Field of Research
Disease Biomarkers, Neuroscience
Purification
Protein G Purified
Concentration
1 mg/ml
Dilution
WB (1:1000), ICC/IF (1:100)
Molecular Weight
550kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
1 μg/ml was sufficient for detection of Piccolo in 20 μg of rat brain tissue lysate by colorimetric immunoblot analysis using goat IgG:HRP as the secondary antibody.
Tested Applications
ELISA, ICC, IF, WB
NCBI Accession Number
NP_001104266.1
Host or Source
Mouse
Preservative
95.46mM Phosphate, 2.48mM MES and 2mM EDTA
Isotype
IgG2b Kappa
Entrez
26875

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