(2R)-Octyl-α-hydroxyglutarate-d17

(2R)-Octyl-α-hydroxyglutarate-d17

• CAS Number: 2748638-78-8
• UNSPSC Description: (2R)-Octyl-α-hydroxyglutarate-d17 ((2R)-Octyl-2-HG-d17) is deuterium labeled (2S)-Octyl-α-hydroxyglutarate. (2S)-Octyl-α-hydroxyglutarate ((2S)-Octyl-2-HG) is a modified form of S-isomer 2-Hydroxyglutarate[1].
• Target Antigen: Isotope-Labeled Compounds; Others
• Type: Isotope-Labeled Compounds
• Related Pathways: Others
• Field of Research: Cancer
• Smiles: OC(CC[C@H](C(OC([2H])(C([2H])(C([2H])(C([2H])(C([2H])(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])[2H])[2H])[2H])[2H])[2H])=O)O)=O
• Molecular Weight: 277.43
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Sulkowski PL, et al. 2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologousrecombination and induces PARP inhibitor sensitivity. Sci Transl Med. 2017 Feb 1;9(375).
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported