(2R)-Octyl-α-hydroxyglutarate-d17

• UNSPSC Description:

  (2R)-Octyl-α-hydroxyglutarate-d17 ((2R)-Octyl-2-HG-d17) is deuterium labeled (2S)-Octyl-α-hydroxyglutarate. (2S)-Octyl-α-hydroxyglutarate ((2S)-Octyl-2-HG) is a modified form of S-isomer 2-Hydroxyglutarate[1].

• Target Antigen:

  Isotope-Labeled Compounds; Others

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Others

• Field of Research:

  Cancer

• Smiles:

  OC(CC[C@H](C(OC([2H])(C([2H])(C([2H])(C([2H])(C([2H])(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])[2H])[2H])[2H])[2H])[2H])=O)O)=O

• Molecular Weight:

  277.43

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Sulkowski PL, et al. 2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologousrecombination and induces PARP inhibitor sensitivity. Sci Transl Med. 2017 Feb 1;9(375).

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2748638-78-8