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(±) -Darifenacin-d4 (hydrobromide)

CAT: 0804-HY-22437S1-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-22437S1-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(±) -Darifenacin-d4 (hydrobromide) is deuterium labeled (±) -Darifenacin. (±) -Darifenacin is the racemate of Darifenacin. Darifenacin is a selective M3 muscarinic receptor antagonist[1].
CAS Number
2747914-16-3
Product Name Alternative
(±) -UK-88525-d4 (hydrobromide)
UNSPSC
12352005
Target
Isotope-Labeled Compounds; mAChR
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Solubility
10 mM in DMSO
Smiles
O=C(C(C1=CC=CC=C1)(C2CN(CC2)C([2H])([2H])C([2H])([2H])C3=CC=C4OCCC4=C3)C5=CC=CC=C5)N.Br
Molecular Formula
C28H27D4BrN2O2
Molecular Weight
511.49
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Hegde SS, et al. Functional role of M2 and M3 muscarinic receptors in the urinary bladder of rats in vitro and in vivo. Br J Pharmacol, 1997, 120 (8), 1409-1418.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
MAChR3

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