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(±) -Darifenacin-d4

CAT: 0804-HY-22437SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-22437SSize:1 mg
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Description
(±) -Darifenacin-d4 is deuterium labeled (±) -Darifenacin. (±) -Darifenacin is the racemate of Darifenacin. Darifenacin is a selective M3 muscarinic receptor antagonist[1].
CAS Number
1189701-43-6
Product Name Alternative
(±) -UK-88525-d4
UNSPSC
12352005
Hazard Statement
H302+H312+H332-H315-H319
Target
Isotope-Labeled Compounds; mAChR
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Solubility
10 mM in DMSO
Smiles
NC(C(C1=CC=CC=C1)(C2=CC=CC=C2)C3CN(CC3)C([2H])([2H])C([2H])([2H])C4=CC=C(OCC5)C5=C4)=O
Molecular Formula
C28H26D4N2O2
Molecular Weight
430.57
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Hegde SS, et al. Functional role of M2 and M3 muscarinic receptors in the urinary bladder of rats in vitro and in vivo. Br J Pharmacol, 1997, 120 (8), 1409-1418.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
MAChR3

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