(±)-Darifenacin-d4

(±)-Darifenacin-d4

• CAS Number: 1189701-43-6
• UNSPSC Description: (±)-Darifenacin-d4 is deuterium labeled (±)-Darifenacin. (±)-Darifenacin is the racemate of Darifenacin. Darifenacin is a selective M3 muscarinic receptor antagonist[1].
• Target Antigen: Isotope-Labeled Compounds; mAChR
• Type: Isotope-Labeled Compounds
• Related Pathways: GPCR/G Protein;Neuronal Signaling;Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer; Neurological Disease
• Solubility: 10 mM in DMSO
• Smiles: NC(C(C1=CC=CC=C1)(C2=CC=CC=C2)C3CN(CC3)C([2H])([2H])C([2H])([2H])C4=CC=C(OCC5)C5=C4)=O
• Molecular Weight: 430.57
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Hegde SS, et al. Functional role of M2 and M3 muscarinic receptors in the urinary bladder of rats in vitro and in vivo. Br J Pharmacol, 1997, 120(8), 1409-1418.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported