MSC-5046

• Description :

  MSC-5046 is a selective TEAD1 inhibitor[1].

• UNSPSC :

  12352005

• Target :

  YAP

• Type :

  Reference compound

• Related Pathways :

  Stem Cell/Wnt

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/msc-5046.html

• Smiles :

  FC(C=N1)=CN2C1=NC=C2C(NCC3=C(CNC(C=C)=O)C(F)=C(OC4=CC=C(F)C=C4)C=C3)=O

• Molecular Formula :

  C24H18F3N5O3

• Molecular Weight :

  481.43

• References & Citations :

  [1]Carswell E, et al. Discovery of reversible and covalent TEAD 1 selective inhibitors MSC-1254 and MSC-5046 based on one scaffold[J]. Bioorganic & Medicinal Chemistry Letters, 2024: 129981.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported