Recombinant mouse IGF-2/IGF-II protein (His tag)

Recombinant mouse IGF-2/IGF-II protein (His tag)

• Background: Insulin-like growth factor I (also known as somatomedin C and somatomedin A) and insulin-like growth factor II (multiplication stimulating activity or MSA) belong to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGF-I and IGF-II share approximately 70% sequence identity. Both IGF-I and IGF-II are expressed in many tissues and cell types and may have autocrine, paracrine and endocrine functions. Mature IGF-I and IGF-II are highly conserved (100% identity between human, bovine and porcine proteins) and exhibit cross-species activity. IGF-II is a potent mitogenic growth factor. However, unlike IGF-I which has important postnatal roles, the growth-promoting function of IGF-II is limited to embryonic development.
• Abbreviation: IGF-2;IGF-II
• Synonyms: IGF-II, Igf2, Insulin-like growth factor II, Multiplication-stimulating polypeptide
• CAS Number: 9000-83-3
• UniProt: P09535
• Accession Number: P09535
• Host: E. coli
• Origin Species: Mouse
• Tag: N-His
• Sequence: Ala 25-Leu 126
• Field of Research: Cancer;Developmental Biology;signal Transduction;Stem Cells
• Purity: > 95% as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
• Molecular Weight: 14 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.