Recombinant Mouse IGF-II protein(His Tag)
CAT:
763-PKSM041521-01
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Recombinant Mouse IGF-II protein(His Tag)
- Background: Insulin-like growth factor I (also known as somatomedin C and somatomedin A) and insulin-like growth factor II (multiplication stimulating activity or MSA) belong to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGF-I and IGF-II share approximately 70% sequence identity. Both IGF-I and IGF-II are expressed in many tissues and cell types and may have autocrine, paracrine and endocrine functions. Mature IGF-I and IGF-II are highly conserved (100% identity between human, bovine and porcine proteins) and exhibit cross-species activity. IGF-II is a potent mitogenic growth factor. However, unlike IGF-I which has important postnatal roles, the growth-promoting function of IGF-II is limited to embryonic development.
- Abbreviation: IGF-II
- Synonyms: AI429687
- CAS Number: 9000-83-3
- UniProt: P09535
- Accession Number: P09535
- Host: E. coli
- Origin Species: Mouse
- Tag: N-His
- Sequence: Ala 25-Glu 91
- Applications: Cell culture
- Purity: > 98 % as determined by reducing SDS-PAGE.
- Bioactivity: Measure by its ability to induce MCF-7 cells proliferation.The ED50 for this effect is <6 ng/mL.The specific activity of recombinant mouse IGF-II is > 1.5 x 105 IU/mg.
- Reconstitution: Please refer to the printed manual for detailed information.
- Molecular Weight: 11 kDa
- Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
- Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.