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Fumagillin

CAT: 0804-HY-B0751-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0751-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Fumagillin (NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.
CAS Number
23110-15-8
Product Name Alternative
Amebacilin; NSC9168
UNSPSC
12352005
Hazard Statement
H302
Target
Antibiotic; HIV; Parasite
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/fumagillin.html
Purity
99.0
Solubility
DMSO : 142.86 mg/mL (ultrasonic)
Smiles
C[C@]1([C@@H](C/C=C(C)/C)O1)[C@]([C@@H]2OC)([H])[C@]3(CC[C@H]2OC(/C=C/C=C/C=C/C=C/C(O)=O)=O)CO3
Molecular Formula
C26H34O7
Molecular Weight
458.54
Precautions
H302
References & Citations
[1]Lefkove, B., B. Govindarajan, and J.L. Arbiser, Fumagillin: an anti-infective as a parent molecule for novel angiogenesis inhibitors. Expert Rev Anti Infect Ther, 2007. 5 (4) : p. 573-9.|[2]Watanabe N, et al. Fumagillin suppresses HIV-1 infection of macrophages through the inhibition of Vpr activity. FEBS Lett. 2006 May 15;580 (11) :2598-602.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Amebae; HIV-1

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