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Hederacoside C (Standard)

CAT: 0804-HY-N0253R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0253R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Hederacoside C (Standard) is the analytical standard of Hederacoside C. This product is intended for research and analytical applications. Hederacoside C (Kalopanaxsaponin B) is an ingredient that can be obtained mainly from ivy leaves. Hederacoside C mediates inflammation by inhibiting activation of MAPK/NF-κB and its downstream signaling pathway. Hederacoside C has anti-inflammatory and antibacterial activity[1][2][3].
CAS Number
14216-03-6
Product Name Alternative
Kalopanaxsaponin B (Standard)
UNSPSC
12352005
Target
Apoptosis; Bacterial; NF-κB; p38 MAPK; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Apoptosis; MAPK/ERK Pathway; NF-κB; Others
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hederacoside-c-standard.html
Smiles
O[C@H]1[C@]([H])(O[C@@H]2[C@@H](O)[C@@H](O)CO[C@]2(O[C@@H]3[C@@](C)(CO)[C@@](CC[C@]4(C)[C@]5([H])CC=C6[C@@]4(C)CC[C@]7(C(O[C@@H]8O[C@H](CO[C@H]9[C@H](O)[C@@H](O)[C@H](O[C@@]%10([H])[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O%10)[C@@H](CO)O9)[C@@H](O)[C@H](O)[C@H]8O)=O)[C@@]6([H])CC(C)(C)CC7)([H])[C@]5(C)CC3)[H])O[C@@H](C)[C@H](O)[C@H]1O
Molecular Formula
C59H96O26
Molecular Weight
1221.38
References & Citations
[1]Zha ZX, et al. Hederacoside C ameliorates colitis via restoring impaired intestinal barrier through moderating S100A9/MAPK and neutrophil recruitment inactivation. Acta Pharmacol Sin. 2023 Jan;44 (1) :105-119.|[2]Akhtar M, et al. Hederacoside-C Inhibition of Staphylococcus aureus-Induced Mastitis via TLR2 & TLR4 and Their Downstream Signaling NF-κB and MAPKs Pathways In Vivo and In Vitro. Inflammation. 2020 Apr;43 (2) :579-594.|[3]Xu HC, et al. Hederacoside-C protects against AGEs-induced ECM degradation in mice chondrocytes. Int Immunopharmacol. 2020 Jul;84:106579.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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