JAK3-IN-6
CAT:
804-HY-101976-01
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
JAK3-IN-6
- CAS Number: 1443235-95-7
- UNSPSC Description: JAK3-IN-6 is a potent, selective irreversible Janus Associated Kinase 3 (JAK3) inhibitor, with an IC50 of 0.15 nM.
- Target Antigen: JAK
- Type: Reference compound
- Related Pathways: Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
- Applications: Neuroscience-Neuromodulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/JAK3-IN-6.html
- Purity: 99.90
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(C1=CNC2=NC=NC(C3=CC=CC(NC(C(C)=C)=O)=C3)=C21)OCC
- Molecular Weight: 350.37
- References & Citations: [1]ARYL SULFONOHYDRAZIDES. WO2017027400A1.|[2]Elwood F, et al. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor. J Pharmacol Exp Ther. 2017 May;361(2):229-244.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported