Indirubin-3'-monoxime

Indirubin-3'-monoxime

• Background: Indirubin-3'-monoxime is an inhibitor of protein kinases and cyclin-dependent kinases. Specifically, it is a potent inhibitor of glycogen synthase kinase-3β (GSK-3β).
• Description: GSK, CDK kinase inhibitor
• Product Name Alternative: Indirubin-3'-monoxime, 3-[1,3-Dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one, Indirubin-3′-oxime
• CAS Number: 160807-49-8
• UNSPSC: 41116105
• Source: Synthetic
• Purity: ≥98% (HPLC)
• Weight: 0.025
• Format: Red solid
• Solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
• Molecular Formula: C16H11N3O2
• Molecular Weight: 277.3
• Precautions: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
• References & Citations: 1. Damiens E., Baratte B., Marie D., Eisenbrand G., & Meijer L. (2001) Oncogene. 20(29): 3786–3797.