Indirubin-3'-monoxime

• Background:

  Indirubin-3'-monoxime is an inhibitor of protein kinases and cyclin-dependent kinases. Specifically, it is a potent inhibitor of glycogen synthase kinase-3β (GSK-3β).

• Description:

  GSK, CDK kinase inhibitor

• Product Name Alternative:

  Indirubin-3'-monoxime, 3-[1,3-Dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one, Indirubin-3′-oxime

• UNSPSC:

  41116105

• Source:

  Synthetic

• Purity:

  ≥98% (HPLC)

• Weight:

  0.025

• Format:

  Red solid

• Solubility:

  Soluble to 100 mM in DMSO and to 100 mM in ethanol

• Molecular Formula:

  C16H11N3O2

• Molecular Weight:

  277.3

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Damiens E., Baratte B., Marie D., Eisenbrand G., & Meijer L. (2001) Oncogene. 20(29): 3786–3797.

• CAS Number:

  160807-49-8