Nutlin-3
CAT:
400-SIH-344-5MG
Size:
5 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Nutlin-3
- Background: MDM2 antagonist; inhibits the MDM2-p53 interaction (IC50 = 0.09 µM) and activates p53. Antiproliferative agent; induces apoptosis in cancer cells.
- Description: p53/mdm2 inhibitor
- Product Name Alternative: (±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5- dihydro-imidazole -1-carbonyl]-piperazin-2-one
- CAS Number: 548472-68-0
- UNSPSC: 41116105
- Source: Synthetic
- Purity: >98%
- Weight: 0.005
- Format: Yellow solid
- Solubility: Soluble in 100 mM DMSO and Ethanol
- Molecular Formula: C30H30Cl2N4O4
- Molecular Weight: 581.9
- Precautions: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- References & Citations: 1. Vassilev et al (2004) Science 303: 844.