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3-Methyladenine

CAT: 0400-SIH-408-100MGSize: 100 mgDry Ice: NoHazardous: No
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CAT#:0400-SIH-408-100MGSize:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
3-Methyladenine inhibits phosphatidylinositol 3-kinase (PI3 kinase) and in doing so also is an inhibitor of autophagy by inhibiting autophagosome formation.
Description
Autophagosome inhibitor
CAS Number
5142-23-4
Product Name Alternative
3-MA, 3-Methyl-3H-purin-6-amine
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cancer | Autophagy
Purity
≥98%
Weight
0.1
Format
White solid.
Solubility
Soluble in DMSO (10 mg/ml) or 100% ethanol (5 mg/ml, warm).
Molecular Formula
C6H7N5
Molecular Weight
149.2
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Blommaart E.F., et al. (1997) Eur J Biochem. 243(1-2): 240-6. 2. Lin Y.C., et al. (2012) J Immunol. 189(8): 4154-64. 3. Wu Y.T., et al. (2010) J Biol Chem. 285(14): 10850-61.

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