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Imatinib mesylate

CAT: 0400-SIH-453-100MGSize: 100 mgDry Ice: NoHazardous: No
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CAT#:0400-SIH-453-100MGSize:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Imatinib mesylate is a tyrosine kinase inhibitor. It specifically inhibits Bcr-Abl tyrosine kinase, and receptor tyrosine kinases encoded by c-kit and platelet-derived growth factor receptor (PDGFR) oncogenes.
Description
Kinase inhibitor
CAS Number
152459-95-5
Product Name Alternative
4-[ (4-Methyl-1-piperazinyl) methyl]-N-[4-methyl-3-[[4- (3-pyridinyl) -2-pyrimidinyl]amino]-phenyl]benzamide methanesulfonate, 4-[ (4-Methylpiperazin-1-yl) methyl]-N- (4-methyl-3-{[4- (pyridin-3-yl) pyrimidin-2-yl]amino}phenyl) benzamide mesylate, CGP 57148, Genfatinib, Glivec, Imatinib methanesulfonate, STI-571
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
≥98% (HPLC)
Weight
0.1
Format
White to beige solid
Solubility
Soluble H2O: soluble10 mg/ml, clear
Molecular Formula
C30H35N7O4S
Molecular Weight
589.7
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Kantarjian H., et al. (2002). N.E. J. Med. 346(9): 645–652.

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