Cytochalasin D

• Background :

  Cytochalasins have the ability to bind to actin filaments and block polymerization and elongation of actin. As a result, they can change cellular morphology, inhibit cellular processes and cause cells to undergo apoptosis (1). Cytochalasin D in particular can inhibit protein synthesis (2).

• Description :

  Actin polymerization inhibitor

• Product Name Alternative :

  (3S,3aR,4S,6S,6aR,7E,10S,12S,13E,15R,15aR) -3-Benzyl-6-hydroxy-4,10,12-trimethyl-5-methylene-1-oxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate, Zygosporin A

• UNSPSC :

  41116105

• Type :

  Inhibitor

• Source :

  Synthetic

• Field of Research :

  Cancer | Apoptosis

• Purity :

  >98% (TLC) ; NMR (Conforms)

• Weight :

  0.005

• Format :

  White Solid

• Solubility :

  Soluble to 10 mM in ethanol and to 50 mM in DMSO

• Molecular Formula :

  C30H37NO6

• Molecular Weight :

  507.63

• Precautions :

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations :

  1.  Haidle A., and Myers A. (2004) Proc Natl Acad Sci. 101(33): 12048-12053. 2. Ornelles et al., (1986) Mol Cell Biol. 6(5): 1650-1662.

• CAS Number :

  22144-77-0