Actinomycin D

• Background :

  The actinomycins are a class of polypeptide antibiotics. Actinomycin D inhibits transcription by binding DNA at the transcription initiation complex and preventing elongation by RNA polymerase (1). Actinomycin D has been used as a chemotherapy drug (2), and an antibiotic.

• Description :

  Transcription inhibitor

• Product Name Alternative :

  2-Amino-N, N'-bis (6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxohexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl) -4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide

• UNSPSC :

  41116105

• Type :

  Inhibitor

• Source :

  Synthetic

• Field of Research :

  Cancer | Apoptosis

• Purity :

  >98%

• Weight :

  0.01

• Format :

  White Solid

• Solubility :

  Soluble to 50 mM in DMSO

• Molecular Formula :

  C62H86N12O16

• Molecular Weight :

  1255.43

• Precautions :

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations :

  1. Sobell H. (1985) Proc Natl Acad Sci USA. 82(16): 5328-31. 2. Turan T., et al. (2006) Int J Gynecol Cancer. 16(3): 1432-1438.

• CAS Number :

  50-76-0