Beta Synuclein Monomers
CAT:
400-SPR-405C
Size:
2x 100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: Yes
Beta Synuclein Monomers
- Background: Alzheimer’s Disease (AD) is the most common neurodegenerative disease, affecting 10% of seniors over the age of 65 (1). It was named after Alois Alzheimer, a German scientist who discovered tangled bundles of fibrils where neurons had once been in the brain of a deceased patient in 1907 (2). Beta synuclein is abundant in neurofibrillary lesions of patients with Alzheimer's Disease. Beta synuclein is suggested to be an inhibitor of alpha synuclein aggregation- protecting the central nervous system from the neurotoxin effects of alpha synuclein (3).
- Description: Human Recombinant Beta Synuclein Protein Monomers
- Product Name Alternative: 14 kDa brain-specific protein, Beta-synuclein Protein, Phosphoneuroprotein 14 Protein, PNP14 Protein, Sncb Protein, Synuclein beta Protein, SYUB_HUMAN Protein
- UNSPSC: 12352202
- Gene ID: 6620
- Swiss Prot: Q16143
- Accession Number: NP_001001502.1
- Cellular Locus: Cytoplasm
- Host: E. coli
- Origin Species: Human
- Target: Beta Synuclein
- Conjugation: No tag
- Applications: WB, SDS-PAGE, In vivo assay, In vitro assay
- Purification Method: Ion-exchange Purified
- Concentration: 2 mg/ml
- Purity: >95%
- Weight: 0.2
- Length: Full length
- Buffer: PBS pH 7.4
- Molecular Weight: 14.28 kDa
- Precautions: Not for use in humans. Not for use in diagnostics or therapeutics. For research use only.
- Additionnal Information: For corresponding PFFs, see catalog# SPR-457
- References & Citations: 1. www.alz.org/alzheimers-dementia/facts-figures 2. Alzheimer, A. Über eine eigenartige Erkrankung der Hirnrinde. Allg. Z. Psychiatr. Psych.-Gerichtl. Med. 64, 146–148 (1907). 3. Taschenberger G., et al. (2013) Ann Neurol. 74(1): 109-118.