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3-O-Methyldopa-d3

CAT: 0804-HY-113468AS-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-113468AS-01Size:1 mg
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Description
3-O-Methyldopa-d3 (3-Methoxy-L-tyrosine-d3) is deuterium labeled 3-O-Methyldopa. 3-O-Methyldopa (3-Methoxy-L-tyrosine) is a metabolite of L-DOPA (HY-N0304) that can cross the blood-brain barrier (BBB). 3-O-Methyldopa inhibits the astrocyte-mediated protective effect of L-DOPA (HY-N0304) on dopaminergic neurons. In addition, 3-O-Methyldopa has certain antidepressant and neuroprotective activities. 3-O-Methyldopa can be used in the research of nervous system diseases such as depression and Parkinson's disease[1].
CAS Number
586954-09-8
Product Name Alternative
3-Methoxy-L-tyrosine-d3; 3-O-Methyl-L-DOPA-d3
UNSPSC
12352005
Target
Drug Metabolite; Interleukin Related; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology; Neurological Disease
Purity
99.9
Solubility
10 mM in DMSO|H2O : 16.67mg/mL (ultrasonic)
Smiles
N[C@@H](CC1=CC=C(O)C(OC([2H])([2H])[2H])=C1)C(O)=O
Molecular Formula
C10H10D3NO4
Molecular Weight
214.23
References & Citations
[1]Masato Asanuma, et al. 3-O-Methyldopa inhibits astrocyte-mediated dopaminergic neuroprotective effects of L-DOPA. BMC Neurosci. 2016 Jul 25;17 (1) :52.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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