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Sakura-6

CAT: 0804-HY-P10029Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P10029Size:1 Each
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Description
Sakura-6 is a SERT-nnos interaction promoter that significantly increases the SERT-nnos complex, but reduces the level of SERT on the cell surface. Acute injection of Sakura-6 into the dorsal raphe nucleus (DRN) causes depression-like behavior in mice[1].
CAS Number
2490708-79-5
UNSPSC
12352209
Target
Serotonin Transporter
Type
Peptides
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sakura-6.html
Solubility
10 mM in DMSO
Smiles
C[C@H](NCCC1CCCCC1)C(N[C@@H](CC(O)=O)C(N[C@H](C(N[C@H](C(O)=O)C(C)C)=O)CC2=CNC3=CC=CC=C23)=O)=O
Molecular Formula
C31H45N5O7
Molecular Weight
599.72
References & Citations
[1]Sun N, et al. Design of fast-onset antidepressant by dissociating SERT from nNOS in the DRN[J]. Science, 2022, 378 (6618) : 390-398.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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